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Babies need folate for the spinal column to develop fully, and the MTHFR variants increase the risk of problems.[ref] This is why prenatal vitamins contain folate and why folic acid is added to white rice and white flour

Journal of clinical oncology: official journal of the American Society of Clinical Oncology

doi: 10.1038/srep07467 114

Target-specific surface-anchored proteins function by taking up free haem or extracting it from haemoproteins in the extracellular medium and delivering it to a TonB-dependent outer membrane receptor (Hariadi et al., 2015)