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Its first-in-human Phase 1b trial (FALCON) dosed its first participant in 2026

Furthermore, the ethical constraints of testing novel therapies in pregnant populations, given potential fetal harm, limit the available translational pathways, exacerbating the gap between preclinical promise and clinical application [68]

209 NF-B receptor activator ligand (RANKL), an osteoclast differentiation factor, has an influential role in osteoclastogenesis, linking the activated immune system to bone loss

Think of it like a tea bag

While the cuprizone diet causes widespread demyelination, removal of cuprizone permits remyelination of the corpus callosum and cerebellar peduncles after a seven-week cuprizone diet [59] or even a longer seven-month diet, although remyelination is less efficient with chronic cuprizone consumption [60]