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None of this means the compound is useless

Overexpression of GSTA1 or treatment with bicyclol significantly decreased the rate of TG synthesis compared to the control (Figure 6B)

After stopping a CYP3A4 inducer, as the effects of the inducer decline, codeine plasma concentrations may increase, with subsequently greater metabolism by cytochrome CYP2D6, resulting in greater morphine levels [see CLINICAL PHARMACOLOGY], which could increase or prolong both the therapeutic effects and adverse reactions, and may cause serious respiratory depression

Moreover, they determined that the total amount of GSH-Px was significantly higher in periodontitis patients than in gingivitis patients [32]