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Low expression of thiamine pyrophosphokinase-1 contributes to brain susceptibility to thiamine deficiency

doi: 10.1016/S1875-5364(14)60110-2 197 YuanQ.SnowD

Qi Y, Zhang X, Wu Z, Tian M, Chen F, Guan W, et al

The methyltransferase Ezh2, responsible for H3K27me3 deposition, synergizes with ERK signaling to promote chromatin condensation and transcriptional activation of EMT-associated genes such as Snail and Twist , thereby enhancing tumor metastatic potential (Lu et al., 2019[76])