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doi: 10.1016/j.ijbiomac.2020.08.222 101 MbembaF.HoubionA.RaesM.RemacleJ

Proc Natl Acad Sci U S A (2012) 109(43):1753742

Metformin acts by increasing cellular AMP-activated protein kinase (AMPK), thereby enhancing peripheral insulin sensitivity and suppressing hepatic gluconeogenesis and glycogenolysis (Alshehri et al