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Chicago, IL: University of Chicago Press

doi: 10.3389/fmed.2025.1535673 Received 27 November 2024 Accepted 25 March 2025 Published 04 April 2025 Volume 12 - 2025 Edited by Vasilios Kotsis, Aristotle University of Thessaloniki, Greece Reviewed by Panagiota Anyfanti, Aristotle University of Thessaloniki, Greece Raina D Ramnath, University of Bristol, United Kingdom Updates Copyright 2025 Wang, Zhang, Qu and Zhou

Nonetheless, its broad-spectrum antibacterial activity can make it an important treatment option when other antibiotics fail or cannot be used

doi: 10.1016/j.exer.2018.11.017 214 GeraMSharmaNGhoshMLeeSJMinTKwonTet al

Drug Interactions The methionine metabolite S-adenosyl methionine (SAM) may interact with antidepressants, antipsychotics, amphetamines, and narcotics causing excess accumulation of serotonin in the body