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found that histone H3K18la can also enhance the transcription of YTHDF2, and YTHDF2 can recognize m6A on PER1 and TP53 mRNA, and promote its degradation, thereby contributing to the development and progression of ocular melanoma [34]

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide composed of 15 amino acids, derived from a partial sequence of body protection compound originally isolated from human gastric juice

In conclusion, these emerging therapeutic approaches offer significant potential for cancer treatment, with lysosomal addiction-based therapies potentially becoming integral components of personalized medical strategies

Therefore, regardless the clinical heterogeneity or underpinning genetics, the different forms of PD share a common etiology in mitochondrial dysfunction and oxidative stress