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1 Introduction Inflammatory bowel disease (IBD) is a chronic, incurable disorder that poses low mortality, stable course, and recurrence, and is a global health problem whose incidence and prevalence are steadily increasing (1)

Discussion The pathways for glutathione synthesis, recycling and metabolism are well established (Figure 6)

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In addition to genetic disease-risks, the identification of genetic disease-modifiers associated with disease complications, severity or prognosis provides crucial insights into the biological processes implicated in disease progression