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Functional instability involves neuromuscular deficits including impaired proprioception, delayed muscle reaction times, and poor motor control that persist even when mechanical structures appear intact

Nagy, L., Kao, H.Y., Love, J.D., Li, C., Banayo, E., Gooch, J.T., Krishna, V., Chatterjee, K., Evans, R.M., Schwabe, J.W

Further results demonstrated that several important inflammatory cytokines, such as interferon (IFN)-, interleukin (IL)-17, and tumor necrosis factor (TNF)-, could be downregulated, H 2 O 2 levels could be decreased, and Th1 and Th17 cell differentiation could be inhibited

Recently, studies have shown that treatment with inflammatory cytokines, such as TNF decreased GLO1 activity in U937 monocytes, which suggested that inflammatory response may be involved in the onset and maintenance of MG excessive accumulation (Hanssen et al., 2014)

This is especially important for patients who worry that losing weight will leave them looking or feeling worse instead of better