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To summarize, IL-23, not IL-12, is the main factor that causes psoriasis

The human gene for the heavy subunit has been localized to chromosome 6p12 [10] and the gene for the light subunit to chromosome 1p21 [11]

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[DOI] [PubMed] [Google Scholar] 1404.Yamakura F, Matsumoto T, Ikeda K, Taka H, Fujimura T, Murayama K, Watanabe E, Tamaki M, Imai T, Takamori K

Introduction Methamphetamine (MA), a central nervous system (CNS) stimulant, is the third most used recreational drug world-wide ( The notion that MA might damage the human brain is derived primarily from preclinical animal data showing that high doses of MA, or its related stimulant amphetamine, cause loss of brain dopamine neuronal markers ( Although the precise mechanism(s) by which high doses of MA cause brain damage in preclinical studies remain uncertain, excessive oxidative stress is a likely candidate