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These studies highlight the potential for developing specific bacteria- and metabolite-based therapeutic interventions to improve outcomes in for example obesity and atherosclerosis

Buckwheat peptides also activate AMPK signaling, which improves fatty acid oxidation, enhances insulin sensitivity, and reduces hepatic lipogenesis, supporting their anti-diabetic potential [37]

Genetic studies have demonstrated that enhanced NRF2 expression significantly attenuates disease progression in EAE models (Kobayashi et al., 2016)

doi: 10.1038/s41419-018-1291-5