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In cognitively healthy individuals, the allele frequencies of ApoE2 , ApoE3 , and ApoE4 are 7, 79, and 14%, respectively, whereas in AD patients, the frequencies are 4, 58, and 38%

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The HP system necessarily responds differently to serum T4 and T3 levels than other tissues, in some persons pathologically so

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To our knowledge, however, no naturally occurring organisms have been described as yet that use such a system constitutively