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To sum up, diet modifications act as a core element for women who are managing Polycystic Ovary Syndrome by tackling all the metabolic, hormonal, and reproductive disorders

Four prominent mechanisms by which mitochondria communicate with the rest of the cell include the release of cytochrome c to induce cell death, activation of AMP-activated protein kinase (AMPK) to control mitochondrial fission and fusion, production of reactive oxygen species (ROS) to activate transcription factors, and the release of mitochondrial DNA (mtDNA) to activate immune responses 2,3,4,5 (Fig

CAF-derived exosomes have been shown to contain amino acids, lipids and TCA intermediates that inhibit mitochondrial oxidative phosphorylation, thereby increasing glutamine-dependent reductive carboxylation and promote glycolysis in tumor cells [149]

The term mTORopathy is used in the context of neurological diseases, especially epileptic encephalopathies and cortical malformations such as tuberous sclerosis due to mutations in TSC1 or TSC2

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