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Extracellular histones exacerbate heat stroke-induced liver injury by triggering hepatocyte pyroptosis and liver injury via the TLR9-NLRP3 pathway

doi: 10.3389/fphys.2015.00203 Received 20 May 2015 Accepted 03 July 2015 Published 22 July 2015 Volume 6 - 2015 Edited by Mauricio Antonio Retamal, Universidad del Desarrollo, Chile Reviewed by Maria Dolores Ledesma, Centro de Biologa Molecular Severo Ochoa (CSIC-UAM), Spain