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ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

Interferon-gamma (IFN-), predominantly produced by natural killer and T cells, exhibits context-dependent immunoregulatory effects in malignancies

Precision medicine in adult and pediatric obesity: a clinical perspective

Instead, patient stratification, biomarker-guided dosing, and careful metabolic phenotyping are likely required to optimize therapeutic benefit while minimizing potential adverse or paradoxical effects