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Perhaps the most compelling argument for ergothioneine's biological importance to humans is the existence of a specific transporter: OCTN1 (SLC22A4)

Even though Bywall et al

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the antibody constructs have a preferred plasma stability (ratio of EC50 with plasma to EC50 w/o plasma) of 5 or 4, more preferably 3.5 or 3, even more preferably 2.5 or 2, and most preferably 1 .5 or 1

Therefore, the extract favors GSHs synthesis and stops its degradation by fighting against the oxidative stress