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One study of tisa-cel-treated patients with LBCL and B-ALL suggested that a higher count of T SCM -like cells in the apheresis, characterized by CD8 + CD45RA + CD27 + expression, was related to the efficacy of CAR-T cell therapy [51]

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doi: 10.1098/rsos.191480 174 LvmoS

The peptide starts the PI3K/Akt and MAPK/ERK pathways that mediate IGF-1s effects on protein synthesis, cell proliferation, glucose body function, and cell survival

In an analysis from The Cancer Genome Atlas, lung cancer patients with high expression of EAAT3 exhibited poor survival rate compared to patients with low EAAT3 expression, thus supporting the notion that EAAT3 is important in lung tumor progression (188)