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A serious clinical complication in these patients is the progressive and frequently late-onset dementia noted in this disorder

(2016) MicroRNA-214 governs lung cancer growth and metastasis by targeting carboxypeptidase-D, DNA Cell Biol

Taken together, some evidence suggests that niacin supplementation may have beneficial effects in migraine patients, but randomized controlled clinical trials are required to determine its clinical implications

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In toxin-induced PD models (e.g., MPTP or MPP + ), these inhibitors protect dopaminergic neurons by suppressing iron-mediated ROS formation, reducing lipid peroxidation, and restoring mitochondrial and synaptic integrity (271, 272)