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J Immunol 180(8):57465753

Cathepsin B activity was determined by measuring Magic red fluorescence intensity filters (excitation: 590 nm, emission: 620 nm) using a Zeiss LSM 880 laser-scanning confocal microscope attached to a Zeiss Observer Z1 microscope using the 60 (numerical aperture: 1.4) oil Plan Apo infinity-corrected optics at 21 C

astrocytes may undergo multiple progressive and/or regressive changes, exhibiting numerous pathological phenotypes that can coexist within the same disorder, be context- or region-specific, or influence one another during disease progression

Therefore, these data indicate a need for de novo synthesis within the time frame of our analyses (Fig