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Vitamin B12 has also proved efficacious in male and female infertility caused by hypovitaminosis B12

Interestingly, pork-based products have significantly lower vitamin B12 content (and iodine), around one-third less, compared with the early 1990s (Niklewicz et al., 2023)

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They could help determine the underlying cause and develop an appropriate treatment plan

The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings