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As with any supplement, there are some possible side effects to B12

doi: 10.3945/ajcn.115.111062, 75

Zhang J, Yang J, Lin C, Liu W, Huo Y, Yang M, et al

The same analysis but combining the subjects from the 4.8 and 7.2 g groups that are not characterized by high oxidative stress did not show changes in GSH-T (medians, V2 = 947.2, V4 = 920.7 mg/L per %Ht, p -value = 0.516) (Figure 4D)