The accession codes for the data sets used are GEO GSE47460, GSE128033, GSE135893, and GSE136831
Bng ng hng khng: 50 n 500kg, nhanh hn v thun tin, vn chuyn n sn bay Bng ng bin: Hn 500kgs, chm hn nhng gi r, vn chuyn n tn cng
The peptide has a molecular weight of 711.868 g/mol (molecular formula CHNO
Use of a mixture consisting of or comprising a) (+)-(2E)-3-(1 ,3-Benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide and b) (-)-(2E)-3-(1 ,3-Benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide, wherein the ratio of the total amount of compound b) and the total amount of compound a) in the mixture is greater than 50 : 50, preferably greater than 75 : 25, preferably greater than 90 : 10, more preferably greater than 95 : 5, more preferably greater than 98 : 2, or of a mixture comprising compound b), wherein the mixture is free of compound a), or of (-)-(2E)-3-(1 ,3-Benzodioxol-5-yl)-N-phenyl-N-(tetrahydro-3-furanyl)-2-propenamide (compound b)) as cooling agent, preferably for in vitro and/or in vivo modulation of the cold and menthol receptor TRPM8, preferably as TRPM8 receptor agonist, and/or for induction of a cold sensation in a human and/or animal, and/or to achieve a cooling effect on the skin or mucosa
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