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Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype

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In addition to intervening fibrosis, TGF- can also influence macrophage-associated anti-inflammatory transition, fibroblast-associated reparative scar formation, and pericyte-associated maturation of infarcted neovessel (Li J

The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro