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Another proof-of-concept trial, meticulously designed as a randomized, double-blind, placebo-controlled study, scrutinized the safety and effectiveness of Rhodiola capsules among 100 individuals grappling with mild to moderate major depressive disorder over a span of 12 weeks

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Meanwhile, methionine enkephalin (MENK), an endogenous opioid peptide, reduces glycolysis and decreases ROS production in MDSCs via the PI3K/AKT/mTOR pathway, thereby inhibiting colon cancer progression (243)

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