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Its role is practical and routine-based rather than short-term or situational

Future studies should prioritize controlled dietary Trp interventions in ICI trials, Phase I/II trials of I3A-loaded engineered probiotics in melanoma, and validation of I3A as a predictive biomarkerpositioning I3A as a prototype for microbiome metabolite-based adjuvants to optimize ICI therapy

At this point of gestation, hepatic conjugative capacity is still immature and may contribute to the greater prevalence, severity, and duration of neonatal jaundice in these infants

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HO, heme-oxygenase