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Patients with COVID-19 may experience a cytokine storm, marked by a significant release of cytokines such as IL-6 and IL-1, resulting in the immune system attacking itself and contributing to fatalities among Sars-Cov-2 patients, see Fig

Nat Commun 17 , 3389 (2026)

To study the joint linear relationship of different variables with oxidative stress variables, complementing the correlation analysis, a multiple linear regression model was performed for each oxidative stress variable in R

Unlike previous reviews, this review emphasizes next-generation probiotics, live biotherapeutics, and genetically engineered microbes, and their synergistic interactions with dietary bioactives such as polyphenols and fibers