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224 Analysis of scRNA-seq and spatial transcriptomics data from paired primary breast cancer tumors and lymph node metastatic tissues revealed that the process of lymph node metastasis in breast cancer involves a metabolic shift from glycolysis to oxidative phosphorylation and back to glycolysis, indicating a potential target for the treatment of tumor metastasis

It not only accumulates inflammatory damage, but also increases cancer cell proliferation and migration (Zhang and Xu, 2018)

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Spiering BA, Kraemer WJ, Vingren JL, Hatfield DL, Fragala MS, Ho J-Y, Maresh CM, Anderson JM, Volek JS