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Using 13 C-NMR, this metabolic flux of lactate from astrocyte to neuron can be measured noninvasively in the human brain (Bouzier-Sore et al., 2007): [mathematical modeling] can give a coherent, quantitative framework for the discussion, suggest possible mechanisms or, conversely, emphasize the contradictions or implausibility or some hypotheses. An example of the argument about the possible ambiguity of mathematical modeling is given by Genc et al

This model is in agreement with data in the literature and with modeling based upon the crystal structure, postulating that an intermediate selenenylsulfide between Cys-59 and Sec-498 is formed

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MCL attenuates atherosclerosis by suppressing macrophage ferroptosis via targeting KEAP1/NRF2 interaction

314,315 Both compositions have demonstrated multi-target activity in NAFLD and are worthy of further continuing clinical trials