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Among the remaining mutations found in our screen, we identified a novel SKN-1 regulator, suco-1 , and a previously identified regulator, elt-3 , as suppressors of SKN-1 activity in amdh-1(uth29) mutant animals (supplemental figure 2c)

Sibilla S, Godfrey M, Brewer S, Budh-Raja A, Genovese L

Utilizaron la puntuacin SYNTAX para cuantificar la carga de aterosclerosis

Genes in the blue module were enriched in various inflammatory response-related biological processes, such as response to lipopolysaccharide and cytokine activity ( Supplementary Figure 2A ), and KEGG analysis revealed significant enrichment in classical RA-related immune-inflammatory pathways such as IL-17 signaling pathway, TNF signaling pathway, and NF-kappaB signaling pathway ( Supplementary Figure 2B ), suggesting that this module may participate in the regulation of pro-inflammatory signaling in RA

Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice