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doi: 10.1016/j.metabol.2020.154272 25 CarusoICignarelliALaviolaLGiorginoF

Diabetologia 63 , 453461 (2020)

The present review aims to elucidate the mechanisms by which copper ions are involved in cardiovascular diseases, summarize the impact of copper ion abnormalities on cardiovascular diseases and potential therapeutic approaches, and investigate whether modulating copper ion levels can ameliorate cardiovascular diseases

Ferroptosis is a key contributor to the development and progression of CVD (9,10)

This destabilization could reduce resilience to environmental perturbations, such as infections or dietary changes, and alter metabolic functions critical for host health (190)