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2025;31(6):e70016

Mammals have 19 Wnt ligands and 10 FZD receptors, leading to a highly complex cascade of signaling responses (Nusse and Clevers, 2017

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This group included known fumarate-related proteins 60 such as MMS19 (a nucleotide excision repair protein) and LIN7C (lin-7 homolog C), and 21 of the 25 proteins were known exosomal components (Fig