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(2020) 18:296270 e6

(38683591) buprenorphine induction via microdoses (micro-induction) buprenorphine induction via microdoses (micro-induction) general concept of micro-induction Traditional strategies for buprenorphine initiation involve cessation of full agonist use, waiting for opioid withdrawal, and then starting buprenorphine (as described in the above section)

Reconstitution comes first

As many as 5% of patients who end up being diagnosed with vitamin B12 deficiency have blood B12 concentrations above a commonly used cut-off of about 150 mol/L, and even more have abnormal methylmalonic acid (MMA) or homocysteine levels, which are signs of functional B12 deficiency even if overt symptoms are not apparent

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