glutathione switch persister cells

glutathione switch persister cells Frontiers Glutathione responsive nanomedicine leverages tumor

Name: glutathione switch persister cells Frontiers Glutathione responsive nanomedicine leverages tumor
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Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics Discover Oncology Springer Nature Link Redox signaling in drug tolerant persister cells as an emerging therapeutic target eBioMedicine How pancreatic cancer survives ferroptosis? Pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations exhibit relative resistance to iron dependent form of cell death, ferroptosis, compared with other tumor types but the mechanisms remain Drug tolerant persister cells in cancer: the cutting edges and future directions Nature Reviews Clinical Oncology Low GPX4 drives a sustained drug tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation ScienceDirect

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doi: 10.1210/en.2012-1558 38 YoungCDLewisASRudolphMCRuehleMDJackmanMRYunUJet al

Studies demonstrate keloids show upregulated p53-serine 15 phosphorylation (p53-pS15), identified through phosphospecific protein microarray and western blotting analysis