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Over the study period, there was an increase in the BTC incidence rate in SEA (APC+0.62)

Never increase more than 100mcg at a time, and allow at least one week at each dose before further adjustment

However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision

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They showed improved endurance times, reduced physical discomfort, faster recovery times after exertion, and improved sleep quality