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In parallel, supercharged NK cells generated through combined cytokine and co-stimulatory receptor signaling have shown strong melanoma control in humanized mice, suggesting an additional route to enhance NK potency with or without CARs [244, 245]

Protection by protein binding of toxic adducts or transition metals (copper or iron) to albumin, transferrin, ferritin, ceruloplasmin or metallothionein, provides another rapid venue for detoxication (liver and systemic circulation)

Antioxid Redox Signal 1: 469-480, 1999 Robak J, Gryglewski RJ: Flavonoids are scavengers of superoxide anions

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These two nutrients work together in the methylation cycle