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The following relevant parameters were determined where possible: area under the concentration-time curve from time zero to the last time point (AUC 0-last ) or extrapolated to infinity (AUC 0- ), C max concentration in plasma extrapolated to time zero (C 0 ), terminal elimination half-life (t 1/2 ), volume of distribution (Vd), and clearance (CL)

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The researchers commented that the peptide suppressed caspase-dependent apoptosis that increases during aging of cell cultures

Additionally, UA has demonstrated neuroprotective effects against oxidative stress caused by hydrogen peroxide (H2O2), thereby safeguarding neuronal survival in the face of elevated levels of reactive oxygen species (ROS) (Figure 5)

Dettling et al., 2025)