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Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds

Leaf senescence and abiotic stresses share reactive oxygen species-mediated chloroplast degradation

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With the stabilisation of the settlement structure, the emergence of feudalism and the establishment of land ownership in the 11th century in what was then Hungary (today's Slovakia), a diversified traditional landscape emerged, which was shaped mainly by the influence of ownership relations

However, whereas one published case report noted a response of RMC to anti-PD-1 immune checkpoint therapy (ICT) with nivolumab 11 , two additional case reports suggested poor efficacy of nivolumab alone or in combination with anti-CTLA-4 blockade using ipilimumab 12