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By increasing solubility, prolonging circulating half-life, and reducing immunogenicity, PEGylation addresses key limitations that have historically constrained the clinical use of peptides

however, further research is needed to elucidate the underlying mechanisms

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Various ion/counter ion salt complexes are contemplated for use herein, including, but not limited to, divalent cations such as calcium, potassium, magnesium, manganese, iron, zinc

The chitin-binding domain allows these peptides to target chitin-containing structures in fungal cell walls, disrupting membrane integrity and inhibiting fungal growth