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Acknowledgements The authors thank Prof Jianbin Xiang (Department of General Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China) for providing colorectal cancer tissues for this study

Kyriakopoulos et al [52] further revealed that APC-100, an antioxidant moiety of -tocopherol, has shown the median progression-free survival of 2.8 months in patients with castrate-resistant prostate cancer

The search terms included NMN, nicotinamide mononucleotide, biotherapy, preclinical studies, animal models, and various specific health conditions (e.g., diabetes, aging, obesity)

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The extender served as the control medium (CON), while treatment groups were supplemented with Nanogreen tea extract (Nano-GTE) at concentrations of 50, 100, 150, and 200 g/mL, respectively