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Assi R, Garcia-Manero G, Ravandi F, Borthakur G , Daver NG, Jabbour E, Burger J, Estrov Z, Dinardo CD, Alvarado Y, Hendrickson S, Ferrajoli A, Wierda W, Cortes J, Kantarjian H, Kadia TM

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It involves initial permeabilization of the mitochondrial outer membrane, followed by an abrupt change in inner membrane permeabilization allowing exit of molecules less than 1500 daltons [89,90]

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