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Environmental factors: Exposure to allergens or toxins can trigger histamine release and affect DAO activity

doi: 10.3390/polym14163352 40 SchwegmannH.FeitzA

5j), likely contributing to DC activation, maturation, and antigen presentation

Histologic and immunopathologic features are the same, although additional findings in pemphigus vulgaris include areas of necrotic keratinocytes (a finding that is more common in paraneoplastic pemphigus) and reactivity to a keratinocytic antigen (110kDa) demonstrated by Western blot.56 Radiation-induced pemphigus vulgaris reactions usually respond well to conventional systemic corticosteroid or other immunosuppressant treatment