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The maintenance of an electric potential across the inner mitochondrial membrane (negatively charged in the matrix) is necessary to power ATP synthase, and sustained decreases in MMP trigger mitophagy and overall decreases in cell viability [98]

A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimers Disease

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Paired-end sequencing (26:98) was performed on the Illumina NextSeq500 platform using NextSeq500/550 High Output v2.5 (150 Cycles) reagents

doi: 10.1016/j.biotechadv.2018.09.003 56 YuYYangWBilottaAJZhaoXCongYLiY