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These physiological responses can accelerate the aging of the skin by breaking down collagen and elastin, leading to the formation of wrinkles and fine lines

1 and 3, are as follows: THF: tetrahydrofolate MS: methionine synthase BHMT: betaine-homocysteine methyltransferase MAT: methionine adenosyltransferase SAM: S-adenosylmethionine SAH: S-adenosylhomocysteine SAHH: SAH hydrolase ADA: adenosine deaminase AK: adenosine kinase CBS: cystathionine beta synthase B12: cyanocobalomine meB12: methylcobalamine 5-CH 3 THF: 5-Methyltetrahydrofolate Claims (5) 1

In other conformations, it chelates with the copper ion (Fig

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Reduced, bioactive form