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621 Astrocytic remodelling in AD also includes an increased synthesis and secretion of GABA: high GABA concentrations were found in astrocytes in animal models and in AD patients

B12 is also essential for the proper functioning of the nervous system, as it helps maintain the health of nerve cells and supports the production of DNA and RNA, the bodys genetic material

Raising intracellular glutathione pools to normal or near normal physiologic levels should theoretically correct many, if not all, of the physiologic and metabolic sequelae of this disorder

Disclosure of interest: Liqun JIao, Yabing Wang, Tao Wang, Jichang Luo, Rixuan Peng, Changchun JIang, Haibo Wang: nonthing to disclose Scientific Communications: life after stroke 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.03 - PROGNOSIS AND OUTCOME AFTER STROKE O - ESOC25-1157 OUTCOMES OF DEPRESSION UP TO 10-YEARS AFTER STROKE: A POPULATION-BASED STUDY Lu Liu 1 , Iain Marshall 1 , Ajay Bhalla 1 , Abdel Douiri 1 , Charles Wolfe 1 , Matthew Dl Oconnell 1 , Yanzhong Wang 1 1 King's College London, London, United Kingdom Background and Aims: Data on the long-term outcomes of post-stroke depression (PSD) are limited

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