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21 These suggested mechanisms improve the energetic metabolism in muscular skeletal tissue, and may have improved muscle function and reduced fatigue and exhaustion

While Acetyl L-Carnitine (ALC) and L-Carnitine share a fundamental role in energy metabolism, several distinct features set them apart

Overexpression of DA D2R in striatal medium spiny neurons specifically induced by a viral vector strategy in adult mice leads to increased behavioral activation and effort expenditure (Trifilieff et al., 2013), while the same overexpression during development leads to the opposite effect with effort discounting (Ward, 2016)