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The previously mentioned diseases are not only the main causes of disability, but also cause death in a short period, thus resulting in loss of the life years.[3] The notion, that obesity is primarily due to individual defects like pleasure-seeking behavior, no self-control or simply being over lazy, is still quite prevalent.[4] At present, the FDA has granted approval for long-term use of five medications against obesity in the United States

(1999) Increased mortality associated with growth hormone treatment in critically ill adults

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For instance, a study by Grace et al., on lambs receiving a single 2 mg subcutaneous B12 injection demonstrated significant increases in serum and liver B12 concentrations for up to 24 days compared to untreated animals (2)