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3rd BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis

These landmark studies showed that mice with adipose-tissue-specific NNMT knockout remained lean when fed high-fat diets that caused wild-type mice to become obese, and that these protected mice had increased energy expenditure, enhanced fatty acid oxidation, improved glucose tolerance, and elevated NAD+ levels in adipose tissue

doi:10.1159/000053183 Wilding JPH, Batterham RL, Calanna S, et al

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