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66 In addition to FOXO, mTORC1, the other downstream signal of the IIS pathway, serves as a central regulator of the mTOR signaling network, promoting cell survival, cell growth and cell cycle progression

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No serious adverse effects of hydroxocobalamin were reported, and many patients with otherwise presumably fatal poisoning survived

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This review summarizes the role of gut microbiota in cardiovascular diseases, highlighting their influence on disease progression and potential therapeutic implications