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For example, the increased dosage of CBS and GCS in our simulation of Down syndrome causes the intracellular concentration of cysteine to decline while the blood concentration increases

Zohny, M

Disruption of this homeostatic equilibrium can lead to dysbiosis and consequent metabolic perturbations that are increasingly implicated in the pathogenesis of chronic conditions such as cancer, cardiometabolic disorders, and IBD (187)

A better understanding of these dynamics may help optimize therapeutic strategies involving hyperbaric oxygen and antioxidant modulation in clinical practice

Niedernhofer LJ, Essers J, Weeda G, Beverloo B, de Wit J, Muijtjens M et al