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Upon ligand binding, the receptors undergo conformational changes that facilitate the recruitment of co-regulatory proteins and their translocation to the nucleus, where they interact with hormone response elements (HREs) to regulate gene transcription (13)

Mass spectrometry is applied to validate the eleven-amino acid sequence and confirm the integrity of residue modifications at receptor selectivity-determining positions

Since every person is different, we always assess lab values individually, taking into account your symptoms and personal situation as well

Mol Pharmacol 80:598609

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